Abnormal hyperactivation in the brain may be an early sign of Alzheimer’s — ScienceDaily

Abnormally hyperactive areas in the brain may help better predict the onset of Alzheimer’s disease, according to findings of a research team led by Université de Montreal psychology professor Sylvie Belleville, scientific Director of the Institut universitaire de gériatrie de Montréal research centre. Hyperactivation could be an early biomarker of Alzheimer’s disease, the researchers say […]

How a very ‘sociable’ protein can hold clues about Alzheimer’s origin

Using the ESRF cryo-electron microscope and Small Angle X-ray Scattering at the ESRF’s beamline BM29, the researchers managed to decipher the role of ECSIT in mitochondrial activity. Credit: ESRF/Stef Candé An international team of scientists led by the ESRF, the European Synchrotron, have found how the ECSIT protein dictates the behavior of proteins linked to […]

New tests identify very early changes in Alzheimer’s disease before symptoms appear

IMAGE: Kaj Blennow, University of Gothenburg, Thomas Karikari, University of Gothenburg, Marc Suarez-Calvet, BBRC, and Henrik Zetterberg, University of Gothenburg. view more  Credit: Photo by University of Gothenburg and BBRC, Spain. Researchers at the University of Gothenburg in Sweden, together with their colleagues at the Barcelona Beta Research Centre in Spain, the University Medical Centre in […]

Early signs of Alzheimer’s disease in people with Down’s syndrome

Researchers at Karolinska Institutet in Sweden have studied the incidence and regional distribution of Alzheimer’s disease biomarkers in the brains of people with Down’s syndrome. The results can bring new possibilities for earlier diagnosis and preventive treatment of dementia. The study is published in Molecular Neurodegeneration. While medical advances and improvements of life quality have […]

Diabetes increases neuritic damage around amyloid plaques in Alzheimer’s disease

New research from the University of Eastern Finland explores the role of diabetes in the cellular and molecular changes underlying Alzheimer’s disease (AD). In an AD mouse model, diabetes induced through a diet rich in fats and sugars weakened the accumulation of microglial cells around amyloid plaques and increased the formation of neuritic plaques with […]

New potential clues in diagnosing, treating Alzheimer’s — ScienceDaily

A study led by the Cedars-Sinai Department of Neurosurgery has identified certain regions in the retina — the lining found in the back of the eye — that are more affected by Alzheimer’s disease than other areas. The findings may help physicians predict changes in the brain as well as cognitive deterioration, even for patients […]

Link between Alzheimer’s disease and gut microbiota is confirmed

Alzheimer’s disease is the most common cause of dementia. Still incurable, it directly affects nearly one million people in Europe, and indirectly millions of family members as well as society as a whole. In recent years, the scientific community has suspected that the gut microbiota plays a role in the development of the disease. A […]