FDA advisory panel declines to support possible Alzheimer’s treatment

The fate of a potential new Alzheimer’s drug is still uncertain. Evidence that the drug works isn’t convincing enough for it to be approved, outside experts told the U.S. Food and Drug Administration during a Nov. 6 virtual meeting that at times became contentious. The scientists and clinicians were convened at the request of the […]

Cause of Alzheimer’s disease traced to mutation in common enzyme

IMAGE: The mutant MARK4 creates a form of tau which accumulates easily in brain cells, causing neurons to die. view more  Credit: Tokyo Metropolitan University Tokyo, Japan – Researchers from Tokyo Metropolitan University have discovered a new mechanism by which clumps of tau protein are created in the brain, killing brain cells and causing Alzheimer’s disease. […]

USC study reveals one-two punch of symptoms that exacerbate Alzheimer’s

A new Alzheimer’s study found that impaired blood flow in the brain is correlated with the buildup of tau tangles, a hallmark indicator of cognitive decline. The work, published this week in the Journal of Neuroscience, suggests that treatments targeting vascular health in the brain — as well as amyloid plaques and tau tangles — […]