Study points the way to boost immunotherapy against breast cancer, other solid tumors

IMAGE: UNC Lineberger Comprehensive Cancer Center’s Jonathan S. Serody, MD, and colleagues report that adding a small molecule to a chimeric antigen receptor-T (CAR-T) cell therapy can help immune system T… view more  Credit: UNC Lineberger Comprehensive Cancer Center CHAPEL HILL, NC–Boosting immune system T cells to effectively attack solid tumors, such as breast cancers, can […]

Combined approach could boost breast cancer immunotherapy, study suggests

IMAGE: A diagram showing the various strategies that could enhance the activity of CAR T cells against breast cancer. view more  Credit: © 2020 Xu et al. Originally published in Journal of Experimental Medicine. https://doi.org/10.1084/jem.20200844 Activating an immune signaling pathway best known for fighting viral and bacterial infections can boost the ability of genetically engineered T […]

Cancer’s intelligence | EurekAlert! Science News

Dr. J. James Frost and The International Journal of Unconventional Computing will soon be publishing “Cancer’s Intelligence” which reports that Cancer can be analyzed as an intelligent system of collaborating and computing cells. The limitations of the current regime of cancer research and treatment are addressed, and the resultant need for new paradigmatic thinking is […]

Enzyme discovery can help rein in blood vessels that fuel cancer

LA JOLLA, CA–Most living things need oxygen to grow and thrive. Even cancerous tumors. That’s why tumors will readily sprout new blood vessels if their oxygen is starved, creating new lifelines for survival. A study published today from Scripps Research pinpoints the precise molecular machinery that makes this happen, providing scientific insights that can potentially […]

Researcher uses machine learning to demonstrate that DNA impacts cancer risk

Lifestyle, or put another way ‘bad habits’, is one of the textbook explanations for why some people are at higher risk for cancer. We often hear that smoking increases our risk of developing lung cancer or that a high-fat diet increases our risk of developing bowel cancer, but not all smokers get lung cancer and […]

New mammogram measures of breast cancer risk could revolutionise screening

World-first techniques for predicting breast cancer risk from mammograms that were developed in Melbourne could revolutionise breast screening by allowing it to be tailored to women at minimal extra cost. Published in the International Journal of Cancer, the University of Melbourne-led study found two new mammogram-based measures of risk. When these measures are combined, they […]

Regulatory RNAs promote breast cancer metastasis

IMAGE: Certain regulatory RNAs are involved in cancer cell movement and metastases. On the right, cancer cells are on the move with long, stiff actin filaments (in green) acting like fingers… view more  Credit: Kung-Chi Chang/Spector lab, 2020 Cold Spring Harbor Laboratory (CSHL) scientists have discovered a gene-regulating snippet of RNA that may contribute to the […]

Physicians don’t always recognize patients’ radiation therapy side effects

IMAGE: Reshma Jagsi, M.D., D.Phil. view more  Credit: University of Michigan Rogel Cancer Center ANN ARBOR, Michigan — Physicians did not recognize side effects from radiation therapy in more than half of breast cancer patients who reported a significant symptom, a new study finds. The study compared reports from 9,941 patients from practices across the state […]