The Phase 3 clinical trial showed that the drug, called CC-486, significantly improved survival in older patients, over the age of 55, with AML — ScienceDaily

A landmark paper published today in the New England Journal of Medicine describes the results from a global trial across 148 sites in 23 countries, showing a 30 per cent improvement in survival in patients with acute myeloid leukemia (AML). The Phase 3 clinical trial called QUAZAR, showed that a drug, called CC-486, significantly improved […]

Study used a ‘search the genome’ approach to reveal how mutations in a gene called UBA1 are associated with inflammatory diseases — ScienceDaily

Researchers from the National Institutes of Health (NIH) have discovered a new inflammatory disorder called vacuoles, E1 enzyme, X-linked, autoinflammatory and somatic syndrome (VEXAS), which is caused by mutations in the UBA1 gene. VEXAS causes symptoms that included blood clots in veins, recurrent fevers, pulmonary abnormalities and vacuoles (unusual cavity-like structures) in myeloid cells. The […]

‘Lost’ tectonic plate called Resurrection hidden under the Pacific

Scientists have reconstructed a long-lost tectonic plate that may have given rise to an arc of volcanoes in the Pacific Ocean 60 million years ago.  The plate, dubbed Resurrection, has long been controversial among geophysicists, as some believe it never existed. But the new reconstruction puts the edge of the rocky plate along a line […]