Fine tuning first-responder immune cells may reduce TBI damage

IMAGE: Drs. Babak Baban (foreground) and Krishnan Dhandapani. view more  Credit: Kim Ratliff, Augusta University photographer AUGUSTA, Ga. (January 25, 2021) – Immediately after a traumatic brain injury and as long as one year later, there are increased levels of immune cells called ILCs in the brain promoting inflammation, which can worsen brain damage, scientists report. […]

University of Cincinnati research unveils possible new combo therapy for head and neck cancer

IMAGE: Christina Wicker, Ph.D., a postdoctoral fellow in the lab of Vinita Takiar, MD, Ph.D., led this research, published in Cancer Letters, which she says will hopefully extend the lives of… view more  Credit: Colleen Kelley/University of Cincinnati Head and neck cancer is the sixth most common cancer worldwide, and while effective treatments exist, sadly, the […]

Regulating the ribosomal RNA production line

IMAGE: A new cryo-EM study shows that the enzyme that makes RNA from a DNA template (RNA polymerase) is altered to slow the production of ribosomal RNA in the bacteria E…. view more  Credit: Murakami Laboratory, Penn State The enzyme that makes RNA from a DNA template is altered to slow the production of ribosomal RNA […]

New variety of paintbrush lily developed by a novel plant tissue culture technique

IMAGE: The steps involved in generating triploid and hexaploid plants by endosperm culture (Photos: Arisa Nakano, Masahiro Mii, Yoichiro Hoshino). view more  Credit: Arisa Nakano, Masahiro Mii, Yoichiro Hoshino Scientists at Hokkaido University and Chiba University have developed simultaneous triploid and hexaploid varieties of Haemanthus albiflos by the application of endosperm culture, thus extending the use […]

New approach emerges to better classify, treat brain tumors

IMAGE: Dr. Jin-Xiong She and MD/PhD student Paul Tran. view more  Credit: Kim Ratliff, Augusta University Photographer AUGUSTA, Ga. (Jan. 19, 2021) – A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence […]

Basis for the essential cellular powerhouses

IMAGE: Model of beta-barrel membrane protein pore biogenesis at the sorting and assembly machinery (SAM) of the outer mitochondrial membrane. view more  Credit: Illustration: Nils Wiedemann Mitochondria are vital for the human body as cellular powerhouses: They possess more than 1,000 different proteins, required for many central metabolic pathways. Disfunction of these lead to severe diseases, […]

Better diet and glucose uptake in the brain lead to longer life in fruit flies

IMAGE: Glucose uptake in brain neurons decreases with age (left), Increasing glucose uptake in brain neurons counteracts aging (middle), Increasing glucose uptake in brain neurons plus dietary restriction further extends lifespan… view more  Credit: Tokyo Metropolitan University Tokyo, Japan – Researchers from Tokyo Metropolitan University have discovered that fruit flies with genetic modifications to enhance glucose […]

New videos show RNA as it’s never been seen

A new Northwestern University-led study is unfolding the mystery of how RNA molecules fold themselves to fit inside cells and perform specific functions. The findings could potentially break down a barrier to understanding and developing treatments for RNA-related diseases, including spinal muscular atrophy and perhaps even the novel coronavirus. “RNA folding is a dynamic process […]

An unexpected, and novel, target for prostate cancer – our biological clock

PHILADELPHIA – Our biological or circadian clock synchronizes all our bodily processes to the natural rhythms of light and dark. It’s no wonder then that disrupting the clock can wreak havoc on our body. In fact, studies have shown that when circadian rhythms are disturbed through sleep deprivation, jet lag, or shift work, there is […]

New treatment allows some people with spinal cord injury to regain hand and arm function

Almost 18,000 Americans experience traumatic spinal cord injuries every year. Many of these people are unable to use their hands and arms and can’t do everyday tasks such as eating, grooming or drinking water without help. Using physical therapy combined with a noninvasive method of stimulating nerve cells in the spinal cord, University of Washington […]