Researchers Are Substantially Undercounting Gene-Editing Errors, Concludes a New Paper

CRISPR Enzyme on DNA

by Jonathan Latham, PhD The standard gene-editing tool, CRISPR-Cas9, frequently produces a type of DNA mutation that ordinary genetic analysis misses, claims new research published in the journal Science Advances. In describing these findings the researchers called such oversights “serious pitfalls” of gene editing (Skryabin et al., 2020). In all, the new results suggest that […]