Researchers reveal the first cryo-EM structures of NSD2 and NSD3 in complex with nucleosome

Credit: Nature The nuclear receptor–binding SET Domain (NSD) family protein is closely connected with many cancers. However, their molecular mechanism remains unknown. Recently, SUSTech research team made new achievements in the study of the cryo-EM structures of NSD2 and NSD3 in complex with nucleosome, which provided molecular insights into the nucleosome based recognition and histone-modification […]