Designer cytokine makes paralyzed mice walk again
The researchers published their report in the Journal Nature Communications from 15 January 2021. When the communication breaks down Spinal cord injuries caused by sports or traffic accidents often result in permanent disabilities such as paraplegia. This is caused by damage to nerve fibers, so-called axons, which carry information from the brain to the muscles […]
Are autism drugs on the horizon?
Recent years have provided substantial research displaying the effect of genetic mu-tations on the development of autism and other neurodevelopmental disorders. Based on those studies, researchers have focused attention on the commonalities be-hind those mutations and how they impact on the functioning of the brain. A study conducted by Professor Sagiv Shifman from the Life […]
Gene therapy strategy found effective in mouse model of hereditary disease TSC
BOSTON – Patients with tuberous sclerosis complex, a genetic disorder characterized by the growth of noncancerous tumors in multiple organs of the body, have limited treatment options. A team led by investigators at Massachusetts General Hospital (MGH) has now shown that gene therapy can effectively treat mice that express one of the mutated genes that […]
New clues to prostate cancer
IMAGE: Flinders University Associate Professor Luke Selth, from the Flinders Health and Medical Research Institute. view more Credit: The Hospital Research Foundation Australian research has identified a new mechanism in which prostate cancer cells can ‘switch’ character and become resistant to therapy. These findings, just published in Cell Reports, are an important development in unravelling how […]
$3.9M project on self-deleting genes takes aim at mosquito-borne diseases
To control mosquito populations and prevent them from transmitting diseases such as malaria, many researchers are pursuing strategies in mosquito genetic engineering. A new Texas A&M AgriLife Research project aims to enable temporary “test runs” of proposed genetic changes in mosquitoes, after which the changes remove themselves from the mosquitoes’ genetic code. The project’s first […]
Scientists at Tel Aviv University develop new gene therapy for deafness
IMAGE: Professor Karen Avraham and Shahar Taiber of Tel Aviv University. view more Credit: Tel Aviv University A new study from Tel Aviv University (TAU) presents an innovative treatment for deafness, based on the delivery of genetic material into the cells of the inner ear. The genetic material “replaces” the genetic defect and enables the cells […]
CRISPR-edited CAR T cells enhance fight against blood cancers
PHILADELPHIA– Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells’ ability to eliminate blood cancers, according to new preclinical data from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn’s Abramson Cancer Center. The findings will […]
Mimicking the effect of exercise with gene therapy
IMAGE: The picture shows heart cells formed by stem cells. The cell nucleus appears blue and stem cells are green. Researchers from the Norwegian University of Science and Technology have identified… view more Credit: Photo: NTNU It sounds too good to be true – and it is. But Jose Bianco Moreira and the CERG research group […]
Scientists develop new gene therapy for eye disease
IMAGE: A fluorescent microscope image with mitochondria highlighted in gold. This healthy cell shows a highly elaborate and well-connected network of mitochondria. view more Credit: Professor Jane Farrar and Dr Daniel Maloney, Trinity College Dublin Scientists from Trinity College Dublin have developed a new gene therapy approach that offers promise for one day treating an eye […]
Cancer’s dangerous renovations to our chromosomes revealed
IMAGE: Chongzhi Zang, PhD, a computational biologist with the University of Virginia’s Center for Public Health Genomics, has revealed the dangerous changes cancer makes to our chromosomes to build itself a… view more Credit: Courtesy Zang lab Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, researchers at the University […]
