Geisinger research identifies genetic risk factor for stroke

DANVILLE, Pa. – A team of Geisinger researchers has identified a common genetic variant as a risk factor for stroke, especially in patients older than 65. Cerebral small vessel disease (SVD) causes about a quarter of ischemic strokes worldwide and is the most common cause of vascular dementia. SVD can manifest as lesions on […]

Study finds rising rates of food insecurity among older adults

From 2007 to 2016, food insecurity–or limited access to nutritious foods because of a lack of financial resources–increased significantly from 5.5% to 12.4% among older US adults, and the increase was more pronounced among individuals with lower income. The findings come from a study published in the Journal of the American Geriatric Society. The study, […]

Global trial reveals life saving drug for acute myeloid leukemia

A landmark paper published today in the New England Journal of Medicine describes the results from a global trial across 148 sites in 23 countries, showing a 30 per cent improvement in survival in patients with acute myeloid leukemia (AML).  The Phase 3 clinical trial called QUAZAR, showed that a drug, called CC-486, significantly improved […]

Discovery of aging mechanism for hematopoietic stem cells

IMAGE: No caption view more  Credit: ©Atsushi IWAMA, The Institute of Medical Science, The University of Tokyo By transferring mouse aged hematopoietic stem cells (aged HSCs, *1) to the environment of young mice (bone marrow niche, *2), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic stem […]

Socioeconomic background linked to survival after having a cardiac arrest in hospital

IMAGE: Graphical abstract view more  Credit: European Heart Journal Hospital in-patients from lower socioeconomic backgrounds are less likely to receive prompt cardiopulmonary resuscitation (CPR) after their hearts stop beating and less likely to survive than patients from higher socioeconomic backgrounds. These are the findings of a new study in over 24,000 patients in Sweden, published in […]

Getting into shape pre-surgery to aid recovery for older patients – study

Older adults about to undergo elective surgery should undertake a sustained programme of targeted exercise beforehand to counteract the muscle-wasting effects of bedrest, new research suggests. A study published by researchers in the University of Birmingham’s School of Sport, Exercise and Rehabilitation Sciences showed that short term ‘prehabilitation’ strength exercises, undertaken pre-surgery, are insufficient to […]

Blood pressure drug may be key to increasing lifespan, new study shows

IMAGE: Scientists found that C. elegans administered metolazone lived longer than those that were not given the drug. This suggests that metolazone, despite being an anti-hypertension drug, can be used in… view more  Credit: Eriko Kage-Nakadai, Osaka City University Since time immemorial, people have been fascinated by ways to stop aging. Nearly every culture has stories […]

Scientists show what loneliness looks like in the brain

This holiday season will be a lonely one for many people as social distancing due to COVID-19 continues, and it is important to understand how isolation affects our health. A new study shows a sort of signature in the brains of lonely people that make them distinct in fundamental ways, based on variations in the […]

Many older adults hospitalized with the flu face persistent functional decline

In a study of older adults admitted to the hospital with influenza and other acute respiratory illnesses during the 2011-2012 flu season, functional decline was common–and for some, this decline was persistent and catastrophic. The findings are published in the Journal of the American Geriatrics Society . Among the 925 patients included in the study, […]