New humanized mouse model provides insight into immunotherapy resistance

IMAGE: Dr. Rajasekharan Somasundaram view more  Credit: The Wistar Institute PHILADELPHIA — (Jan. 12, 2021) — Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for mast cells. These findings were published […]