Scientists reveal mechanism that causes irritable bowel syndrome — ScienceDaily

KU Leuven researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study, carried out in mice and humans, was published in Nature. Up to 20% of the […]

New mechanism underlying male infertility — ScienceDaily

One essential component of each eukaryotic cell is the cytoskeleton. Microtubules, tiny tubes consisting of a protein called tubulin, are part of this skeleton of cells. Cilia and flagella, which are antenna-like structures that protrude from most of the cells in our body, contain many microtubules. An example of flagell is the sperm tail, which […]

Understanding nanoparticle entry mechanism into tumors

Announcing a new publication for BIO Integration journal. In this commentary the authors Phei Er Saw and Sangyong Jon from Sun Yat-Sen University, Guangzhou, China and the Korea Advanced Institute of Science and Technology, Daejeon, Korea, consider how the entry mechanism of nanoparticles into tumors determines the future direction of nanomedicine development. Enhanced permeability and […]

Discovery of aging mechanism for hematopoietic stem cells

IMAGE: No caption view more  Credit: ©Atsushi IWAMA, The Institute of Medical Science, The University of Tokyo By transferring mouse aged hematopoietic stem cells (aged HSCs, *1) to the environment of young mice (bone marrow niche, *2), it was demonstrated that the pattern of stem cell gene expression was rejuvenated to that of young hematopoietic stem […]

Experts develop new mechanism that can trap submicron particles in minutes

The researchers found salt acted similarly to a magnet. Credit: Loughborough University A spoonful of sugar may make the medicine go down, but a new Loughborough-led study suggests a dash of salt is key to progressing important medical areas such as drug delivery and biological sample analysis. Naval Singh, a Ph.D. student in the University’s […]

New mechanism of pain control revealed — ScienceDaily

Researchers in Japan have revealed a previously unknown mechanism for pain control involving a newly identified group of cells in the spinal cord, offering a potential target for enhancing the therapeutic effect of drugs for chronic pain. While neurons may be the most well-known cells of the central nervous system, an assortment of non-neuronal cells […]

The CNO energy-production mechanism in the universe is detected — ScienceDaily

An international team of about 100 scientists of the Borexino Collaboration, including particle physicist Andrea Pocar at the University of Massachusetts Amherst, report in Nature this week detection of neutrinos from the sun, directly revealing for the first time that the carbon-nitrogen-oxygen (CNO) fusion-cycle is at work in our sun. The CNO cycle is the […]

New mechanism of pain control revealed

IMAGE: Research out of Kyushu University has shown that a unique population of astrocytes, marked with bright yellow here, in the dorsal horn of the mouse spinal cord can be activated… view more  Credit: Makoto Tsuda, Kyushu University Researchers in Japan have revealed a previously unknown mechanism for pain control involving a newly identified group of […]

Once-discounted binding mechanism may be key to targeting viruses — ScienceDaily

“Position 4” didn’t seem important until researchers took a long look at a particular peptide. That part of the peptide drawn from a SARS-CoV virus turned out to have an unexpected but significant influence on how it stably binds with a receptor central to the immune system’s ability to attack diseased cells. In a study […]

Researchers discover mechanism that allows SINEUPs to amplify protein production

Scientists from an international group led by the RIKEN Center for Integrative Medical Sciences and Yokohama City University have discovered that a pair of proteins play a key role in allowing an important type of functional non-coding RNA, known as SINEUPs, to act to promote their target messenger RNA.SINEUPs are a recently discovered type of […]