Cancer vaccine helped keep melanoma under control for years in small study

A personalized “cancer vaccine” may help keep a deadly form of skin cancer from growing for years, a small new study in humans suggests. Unlike vaccines that prevent infections, such as measles and influenza, cancer vaccines are a form of immunotherapy that take down cancer cells that already exist. The vaccines train immune cells, called […]

Texas A&M research explores how melanoma grows and spreads

The first step in treating cancer is understanding how it starts, grows and spreads throughout the body. A relatively new cancer research approach is the study of metabolites, the products of different steps in cancer cell metabolism, and how those substances interact. To date, research like this has focused mostly on cancerous tissues; however, normal […]

An epidemic of overdiagnosis: Melanoma diagnoses sky rocket

WHO H. Gilbert Welch MD, MPH, Senior Investigator, Center for Surgery and Public Health, Brigham and Women’s Hospital; co-author of a new Sounding Board article published in The New England Journal of Medicine. WHAT Melanoma of the skin is now the third most commonly diagnosed cancer in the U.S. Diagnoses of melanoma are six times […]

Aggressive melanoma cells at edge of tumours are key to cancer spread

Research led by Queen Mary University of London has revealed novel insights into the mechanisms employed by melanoma cells to form tumours at secondary sites around the body. The findings from the study may help to identify new targets to inhibit melanoma spread and guide treatment decisions in the clinic. Melanoma is an aggressive type […]

ctDNA may predict outcomes with first-line, but not second-line immunotherapy for melanoma

Bottom Line: Baseline levels of circulating tumor DNA (ctDNA) predicted responses to first-line, but not second-line, immune checkpoint inhibition in patients with melanoma. Journal in Which the Study was Published: Clinical Cancer Research, a journal of the American Association for Cancer Research Author: Elin Gray, PhD, an associate professor at Edith Cowan University in Australia […]

A promising new tool in the fight against melanoma

IMAGE: Edith Cowan University Associate Professor Elin Gray view more  Credit: Edith Cowan University An Edith Cowan University (ECU) study has revealed that a key blood marker of cancer could be used to select the most effective treatment for melanoma. The discovery, which has the potential to improve melanoma survival rates, was published today in Clinical […]