NSAIDs might exacerbate or suppress COVID-19 depending on timing, mouse study suggests

Washington, DC – January 22, 2021 – New research shows that non-steroidal anti-inflammatory drugs (NSAIDs) reduced both antibody and inflammatory responses to SARS-CoV-2 infection in mice. The study appears this week in the Journal of Virology, a publication of the American Society for Microbiology. The research is important because “NSAIDs are arguably the most commonly […]

Rediscovery of the ‘extinct’ Pinatubo volcano mouse

The rediscovered volcano mouse, thought to be extinct. Credit: Danny Balete, Field Museum In June 1991, Mount Pinatubo, a volcanic peak on the Philippine Island of Luzon, literally blew its top. It was the second-most powerful volcanic eruption of the 20th century, ten times stronger than Mount Saint Helens, and its effects were devastating. Lava […]

NSAIDs might exacerbate or suppress COVID-19 depending on timing, mouse study suggests — ScienceDaily

New research shows that non-steroidal anti-inflammatory drugs (NSAIDs) reduced both antibody and inflammatory responses to SARS-CoV-2 infection in mice. The study appears this week in the Journal of Virology, a publication of the American Society for Microbiology. The research is important because “NSAIDs are arguably the most commonly used anti-inflammatory medications,” said principal investigator Craig […]

New humanized mouse model provides insight into immunotherapy resistance

IMAGE: Dr. Rajasekharan Somasundaram view more  Credit: The Wistar Institute PHILADELPHIA — (Jan. 12, 2021) — Scientists at The Wistar Institute have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for mast cells. These findings were published […]

Gene therapy strategy found effective in mouse model of hereditary disease TSC

BOSTON – Patients with tuberous sclerosis complex, a genetic disorder characterized by the growth of noncancerous tumors in multiple organs of the body, have limited treatment options. A team led by investigators at Massachusetts General Hospital (MGH) has now shown that gene therapy can effectively treat mice that express one of the mutated genes that […]

Mouse study finds link between gut disease and brain injury in premature infants — ScienceDaily

Physicians have long known that necrotizing enterocolitis (NEC), a potentially lethal inflammatory condition that destroys a premature infant’s intestinal lining, is often connected to the development of severe brain injury in those infants who survive. However, the means by which the diseased intestine “communicates” its devastation to the newborn brain has remained largely unknown. Now, […]

Best gaming mouse: What to look for when buying this accessory

Upgrade your mouse option for smoother gameplay. (Emmanuel via Unsplash/) Any PC gamer knows that finding the best gaming mouse is paramount to your setup. A good gaming mouse determines how precise, quick, and accurate your various strikes, selections, and sudden moves will be. A regular computer mouse isn’t built to handle rapid movement or […]

3D cell culturing technique could replace mouse embryos — ScienceDaily

By growing mouse stem cells in a special gel, a Berlin research team succeeded to grow structures similar to parts of an embryo. The trunk-like structures develop the precursors for neural, bone, cartilage and muscle tissues from cellular clumps within five days. This could allow the investigation of the effects of pharmacological agents more effectively […]

Gene-Editing Unintentionally Adds Bovine DNA, Goat DNA, and Bacterial DNA, Mouse Researchers Find – Independent Science News

An animal research facility

by Jonathan Latham, PhD The gene-editing of DNA inside living cells is considered by many to be the preeminent technological breakthrough of the new millennium. Researchers in medicine and agriculture have rapidly adopted it as a technique for discovering cell and organism functions. But its commercial prospects are much more complicated. Gene-editing has many potential […]