Near-atomic ‘maps’ reveal structure for maintaining pH balance in cells — ScienceDaily

For the first time, scientists have visualized a new class of molecular gates that maintain pH balance within brain cells, a critical function that keeps cells alive and helps prevent stroke and other brain injuries. These gates, called proton-activated chloride channels (PAC), nest within cell membranes and regulate the passage of small molecules called chloride […]

Near-atomic ‘maps’ reveal structure for maintaining pH balance in cells

Cryo-EM images of proton-activated chloride channel (PAC). Credit: Dr. Wei Lü, Van Andel Institute For the first time, scientists have visualized a new class of molecular gates that maintain pH balance within brain cells, a critical function that keeps cells alive and helps prevent stroke and other brain injuries. These gates, called proton-activated chloride channels […]