Nucleic circ2082 disrupts the microRNA assembly line in glioblastoma cancer cells, making it a potential upstream target for cancer treatment — ScienceDaily

Like Peter Pan, some cells never grow up. In cancer, undifferentiated stem cells may help tumors such as glioblastoma become more aggressive than other forms of the disease. Certain groups of genes are supposed to help cells along the path to maturity, leaving their youthful “stemness” behind. This requires sweeping changes in the microRNAome — […]

New test method to standardize immunological evaluation of nucleic acid nanoparticles

Schematic summary of the experimental flow. Credit: Melina Richardson (Afonin Lab, UNC Charlotte) Therapeutic nucleic acids—lab-created segments of DNA or RNA, designed be used to block or modify genes, control gene expression or regulate other cellular processes—are a promising but still emerging area of biomedical treatment, with several drugs already in use and many more […]

New test method to standardize immunological evaluation of nucleic acid nanoparticles

IMAGE: Schematic summary of the experimental flow. view more  Credit: Melina Richardson (Afonin Lab, UNC Charlotte) Therapeutic nucleic acids – lab-created segments of DNA or RNA, designed be used to block or modify genes, control gene expression or regulate other cellular processes – are a promising but still emerging area of biomedical treatment, with several drugs […]