Scientists discover a new promising target for diabetes treatment

IMAGE: Model of insulin inhibitory receptor ‘inceptor’ (in black) desensetizing the insulin recptor (in color) on a pancreatic beta cell. Insulin in blue. view more  Credit: Helmholtz Zentrum München Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The latest study from Helmholtz Zentrum Muenchen, the Technical University of Munich and the German […]

Rhesus macaques develop promising immune response to SARS-CoV-2

In a promising result for the success of vaccines against COVID-19, rhesus macaque monkeys infected with the human coronavirus SARS-CoV-2 developed protective immune responses that might be reproduced with a vaccine. The work was carried out at the California National Primate Research Center at the University of California, Davis and is published Jan. 22 in […]

Case study shows promising proof of concept for ongoing clinical trial — ScienceDaily

Targeted neuromodulation tailored to individual patients’ distinctive symptoms is an increasingly common way of correcting misfiring brain circuits in people with epilepsy or Parkinson’s disease. Now, scientists at UC San Francisco’s Dolby Family Center for Mood Disorders have demonstrated a novel personalized neuromodulation approach that — at least in one patient — was able to […]

NIH neuroscientists isolate promising mini antibodies against COVID-19 from a llama

IMAGE: NIH scientists showed that anti-COVID-19 nanobodies from a llama may be an effective tool in the battle against the COVID-19 virus. view more  Credit: Courtesy of Brody lab NIH/NINDS. National Institutes of Health researchers have isolated a set of promising, tiny antibodies, or “nanobodies,” against SARS-CoV-2 that were produced by a llama named Cormac. Preliminary […]

Promising treatment for premenstrual dysphoric disorder, PMDD

The mental symptoms of premenstrual dysphoric disorder improve following treatment with a progesterone receptor modulator, as demonstrated by SciLifeLab researcher Erika Comasco and Professor Inger Sundström-Poromaa, Uppsala University. The mechanism of action of the study drug provides insights into the potential molecular mechanisms underlying this psychiatric disorder and its treatment. It has long been known […]

Here are the most promising coronavirus vaccine candidates out there

Editor’s Note: This story was updated on Nov. 25. Using materials from weakened cold viruses to snippets of genetic code, scientists around the world are creating dozens of unique vaccine candidates to fight the novel coronavirus — and they’re doing it at unprecedented speeds. It’s not known exactly when the virus hopped from animals to […]

Promising MS drug may worsen disease — ScienceDaily

A drug that has shown promise for treating multiple sclerosis may actually make the debilitating disease worse, new research from the University of Virginia School of Medicine suggests. The drug has not yet made it to human trials for MS, but the UVA scientists are warning their fellow researchers to proceed extremely cautiously. In addition […]

A Promising Development for Detecting Ocean Productivity

The ocean’s primary productivity—the pace at which organisms photosynthesize organic compounds—is an integral part of the global carbon cycle that affects the cycling of important nutrients and trace metals in marine ecosystems. Ocean primary productivity also controls carbon dioxide exchange between the air and the sea, which in turn affects the concentration of […]

Agent shows promising results in nonhuman primates — ScienceDaily

Researchers have validated a new radiolabeled molecule that can be used with imaging tests to accurately detect and characterize brain injury. The team, led by investigators at Massachusetts General Hospital (MGH), recently received clearance from the U.S. Food and Drug Administration (FDA) to initiate a first-in-human study with the strategy. As described in the Journal […]