COVID-19 severity affected by proportion of antibodies targeting crucial viral protein

COVID-19 antibodies preferentially target a different part of the virus in mild cases of COVID-19 than they do in severe cases, and wane significantly within several months of infection, according to a new study by researchers at Stanford Medicine. The findings identify new links between the course of the disease and a patient’s immune response. […]

Preexisting antibodies targeting SARS-CoV-2 discovered in small proportion of uninfected individuals

Scientists have detected preexisting antibody-driven immunity against SARS-CoV-2 in a small proportion of individuals who were uninfected at the time of sampling. Sixteen out of 302 adults (5.3%) harbored IgG antibodies that were likely generated during previous seasonal “common cold” coronavirus infections, and which cross-reacted with subunit S2 of the SARS-CoV-2 spike protein complex. Notably, […]