UC researcher urges caution using remdesivir to treat COVID-19

IMAGE: Bingfang Yan is a professor at the University of Cincinnati’s James L. Winkle College of Pharmacy. Yan’s UC laboratory studies how drugs are metabolized in the body to see if… view more  Credit: University of Cincinnati While the world has its eyes on vaccines to stop the spread of coronavirus, therapeutics are still necessary to […]

In lab experiments, pralatrexate outperforms remdesivir against SARS-CoV-2 — ScienceDaily

A novel computational drug screening strategy combined with lab experiments suggest that pralatrexate, a chemotherapy medication originally developed to treat lymphoma, could potentially be repurposed to treat Covid-19. Haiping Zhang of the Shenzhen Institutes of Advanced Technology in Shenzhen, China, and colleagues present these findings in the open-access journal PLOS Computational Biology. With the Covid-19 […]

The WHO and FDA are at odds over remdesivir

Over 50 million American plan on traveling for Thanksgiving. (Camila Perez/) As health officials have been warning for months, the cold weather and holiday season have resulted in intense, widespread spikes in COVID-19 infections across the country. The US saw one million new cases last week, and that number is expected to continue climbing as […]

WHO Guideline Development Group advises against use of remdesivir for covid-19

The antiviral drug remdesivir is not suggested for patients admitted to hospital with covid-19, regardless of how severely ill they are, because there is currently no evidence that it improves survival or the need for ventilation, say a WHO Guideline Development Group (GDG) panel of international experts in The BMJ today. The recommendation is part […]

Remdesivir has ‘no meaningful impact’ on COVID-19 survival, huge study finds

The antiviral drug remdesivir does not reduce deaths among COVID-19 patients, as compared with standard care, according to the results of a large, international trial. The Food and Drug Administration, in May, authorized remdesivir to be used in an emergency to treat COVID-19, after a large clinical trial suggested that the drug reduces the time […]

Remdesivir doesn’t reduce COVID-19 deaths, a large WHO trial finds

Remdesivir, an antiviral drug that was the first found to combat COVID-19, doesn’t reduce deaths from the disease, a large international study found. The World Health Organization’s Solidarity trial, which combined data from 405 hospitals in 30 countries, randomly assigned more than 11,000 people hospitalized with COVID-19 to receive one of four drugs or standard […]