ECMO/CRRT in the treatment of critically ill SARS-CoV-2 pneumonia patients

In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.1267, Hai Zou and Shengqing Li from the Institute of Pulmonary and Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai, China consider ECMO/CRRT combined support in the treatment of critically ill SARS-CoV-2 pneumonia patients. The authors of this article explored the experience with, and complications […]

Rhesus macaques develop promising immune response to SARS-CoV-2

In a promising result for the success of vaccines against COVID-19, rhesus macaque monkeys infected with the human coronavirus SARS-CoV-2 developed protective immune responses that might be reproduced with a vaccine. The work was carried out at the California National Primate Research Center at the University of California, Davis and is published Jan. 22 in […]

SARS-CoV-2 infection demonstrated in a human lung bronchioalveolar tissue model

Heidelberg/Germany, 11 January 2021 – Development of an in vitro human-derived tissue model for studying virus infection and disease progression in the alveolar cells of the lungs responsible for oxygen and carbon dioxide exchange with the blood might enable the study of possible therapies for acute respiratory distress syndrome (ARDS) triggered by SARS-CoV-2. Researchers in […]

Results of comprehensive SARS-CoV-2 animal model study published in Nature Microbiology

San Antonio, Texas (January 4, 2020) – Scientists at Texas Biomedical Research Institute (Texas Biomed) and Southwest National Primate Research Center (SNPRC) published their findings regarding a comprehensive animal model study of SARS-CoV-2 in the peer-reviewed journal Nature Microbiology. These findings were originally posted online in BioRxiv in June of 2020. The study evaluated three […]

In lab experiments, pralatrexate outperforms remdesivir against SARS-CoV-2 — ScienceDaily

A novel computational drug screening strategy combined with lab experiments suggest that pralatrexate, a chemotherapy medication originally developed to treat lymphoma, could potentially be repurposed to treat Covid-19. Haiping Zhang of the Shenzhen Institutes of Advanced Technology in Shenzhen, China, and colleagues present these findings in the open-access journal PLOS Computational Biology. With the Covid-19 […]

Assessment of air contamination by SARS-CoV-2 in hospital settings

What The Study Did: In this systematic review of current evidence on air contamination with SARS-CoV-2 in hospital settings, the air close to and distant from patients with COVID-19 was frequently contaminated with SARS-CoV-2 RNA; however, few of these samples contained viable viruses. High viral loads found in toilets and bathrooms, staff areas and public hallways suggest […]

1st wild animal in US infected with SARS-CoV-2 found in Utah

A wild mink in Utah tested positive for SARS-CoV-2, the virus that causes COVID-19, and it may be the first “free-ranging, native wild animal” with a confirmed coronavirus infection, according to the U.S. Department of Agriculture (USDA). There’s no evidence that the virus spread further than this one infected mink, but if SARS-CoV-2 begins circulating […]

High-speed model for the fight against SARS-CoV2

Four spike proteins on the membrane surface of sars-CoV-2. If these proteins bind to ACE2 receptors on the cell surface, the virus can enter the cells and replicate. Credit: MPI f. Biophysics/ von Bülow, Sikora, Hummer To contain the SARS-CoV2 coronavirus and slow the spread of infections and the rising death toll, researchers and health […]

Studies reveal potential weaknesses in SARS-CoV-2 infection

A single protein that appears necessary for the COVID-19 virus to reproduce and spread to other cells is a potential weakness that could be targeted by future therapies. The molecule, known as transmembrane protein 41 B (TMEM41B), is believed to help shape the fatty outer membrane that protects the virus’ genetic material while it replicates […]