UCLA scientists develop high-throughput mitochondria transfer device

LOS ANGELES — Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially treat debilitating diseases such as cancer, diabetes and metabolic disorders. […]

Scientists develop high-throughput mitochondria transfer device

Mitochondrial DNA. Credit: en.wikipedia.org Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially treat debilitating diseases such as cancer, diabetes and metabolic […]

Scientists develop high-throughput mitochondria transfer device — ScienceDaily

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells. This approach enables researchers to tailor a key genetic component of cells, to study and potentially treat debilitating diseases such as cancer, diabetes and metabolic disorders. A study, published […]

Research reveals compromised transfer of SARS-CoV-2-specific antibodies through placenta

BOSTON – Recent analyses indicate that pregnant women and newborns may face elevated risks of developing more severe cases of COVID-19 following SARS-CoV-2 infection. New research led by investigators at Massachusetts General Hospital (MGH) and published in Cell reveals lower than expected transfer of protective SARS-CoV-2 antibodies via the placenta from mothers who are infected […]

Chemists characterize key compound for catalytic nitrogen atom transfer — ScienceDaily

Catalysts with a metal-nitrogen bond can transfer nitrogen to organic molecules. In this process short-lived molecular species are formed, whose properties critically determine the course of the reaction and product formation. The key compound in a catalytic nitrogen-atom transfer reaction has now been analysed in detail by chemists. The detailed understanding of this reaction will […]

Dynamic photonic barcodes record energy transfer at the biointerface

Dynamic photonic barcodes enable molecular detection. Credit: Zhou et al., doi 10.1117/1.AP.2.6.066002 Optical barcodes enable detection and tracking via unique spectral fingerprints. They’ve been widely applied in areas ranging from multiplexed bioassays and cell tagging to anticounterfeiting and security. Yu-Cheng Chen of the Bio+Intelligent Photonics Laboratory at Nanyang Technological University notes that the concept of […]

Cavity-enhanced radiative energy transfer converts biomolecular information from a single droplet into trillions of distinctive photonic barcodes — ScienceDaily

Optical barcodes enable detection and tracking via unique spectral fingerprints. They’ve been widely applied in areas ranging from multiplexed bioassays and cell tagging to anticounterfeiting and security. Yu-Cheng Chen of the Bio+Intelligent Photonics Laboratory at Nanyang Technological University notes that the concept of optical barcodes typically refers to a fixed spectral pattern corresponding to a […]

Novel adoptive cell transfer method shortens timeline for T-cell manufacture

IMAGE: A faster approach for T-cell therapy against cancer. Knochelmann and colleagues show a subset of CD4 T-cells, Th17 cells, can effectively kill tumor cells when they are grown in cell… view more  Credit: MUSC Hollings Cancer Center Adoptively transferred T-cells can prolong survival and sometimes cure patients with advanced solid tumors. While promising, it can […]