Scientists discover a new promising target for diabetes treatment

IMAGE: Model of insulin inhibitory receptor ‘inceptor’ (in black) desensetizing the insulin recptor (in color) on a pancreatic beta cell. Insulin in blue. view more  Credit: Helmholtz Zentrum München Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The latest study from Helmholtz Zentrum Muenchen, the Technical University of Munich and the German […]

ECMO/CRRT in the treatment of critically ill SARS-CoV-2 pneumonia patients

In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.1267, Hai Zou and Shengqing Li from the Institute of Pulmonary and Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai, China consider ECMO/CRRT combined support in the treatment of critically ill SARS-CoV-2 pneumonia patients. The authors of this article explored the experience with, and complications […]

Combination treatment for methamphetamine use disorder shows promise — ScienceDaily

A combination of two medications, injectable naltrexone and oral bupropion, was safe and effective in treating adults with moderate or severe methamphetamine use disorder in a double-blind, placebo-controlled Phase III clinical trial. The findings suggest this combination therapy may be a promising addition to current approaches to treatment, such as cognitive behavioral therapy and contingency […]

Scientists study use of abundant enzyme in tumor cells to monitor cancer treatment

IMAGE: The team led by Carmen Ferreira-Halder at Unicamps Bioassay and Signal Tranduction Laboratory conclude that the molecule is associated with chemotherapy resistance and metastasis. view more  Credit: Roberta Ruela de Souza The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator […]

New treatment allows some people with spinal cord injury to regain hand and arm function

Almost 18,000 Americans experience traumatic spinal cord injuries every year. Many of these people are unable to use their hands and arms and can’t do everyday tasks such as eating, grooming or drinking water without help. Using physical therapy combined with a noninvasive method of stimulating nerve cells in the spinal cord, University of Washington […]

Nucleic circ2082 disrupts the microRNA assembly line in glioblastoma cancer cells, making it a potential upstream target for cancer treatment — ScienceDaily

Like Peter Pan, some cells never grow up. In cancer, undifferentiated stem cells may help tumors such as glioblastoma become more aggressive than other forms of the disease. Certain groups of genes are supposed to help cells along the path to maturity, leaving their youthful “stemness” behind. This requires sweeping changes in the microRNAome — […]