Cell atlas of tropical disease parasite may hold key to new treatments

The first cell atlas of an important life stage of Schistosoma mansoni, a parasitic worm that poses a risk to hundreds of millions of people each year, has been developed by researchers at the Wellcome Sanger Institute and their collaborators. The study, published today (18 December 2020) in Nature Communications, identified 13 distinct cell types […]

Genes could be key to new COVID-19 treatments, study finds — ScienceDaily

Potential treatments for Covid-19 have been identified after the discovery of five genes associated with the most severe form of the disease. Genetic evidence is second only to clinical trials as a way to tell which treatments will be effective in a disease. Existing drugs that target the actions of the genes reveal which drugs […]

The best treatments we currently have for COVID-19

Empty hospital beds have been an uncommon sight during this pandemic. (Pexels/) Follow all of PopSci’s COVID-19 coverage here, including the truth about herd immunity, advice for pregnant women, and a tutorial on making your own mask. The first doses of a COVID-19 vaccine have been given, and hope for the eventual end of the […]

New insights about age-related macular degeneration could spur better treatments

BOSTON – “Wet” age-related macular degeneration (AMD) is one of the most common causes of irreversible vision loss in the elderly, and it occurs when abnormal and leaky blood vessels form in the retina, in part due to inflammation. New research by investigators at Massachusetts General Hospital (MGH) reveals insights into potential drivers of the […]

Genes could be key to new COVID-19 treatments, study finds

Potential treatments for Covid-19 have been identified after the discovery of five genes associated with the most severe form of the disease. Genetic evidence is second only to clinical trials as a way to tell which treatments will be effective in a disease. Existing drugs that target the actions of the genes reveal which drugs […]

Venetoclax added to standard treatments shows promise in high-risk myeloid blood cancers

IMAGE: Jacqueline Garcia, MD view more  Credit: Dana-Farber Cancer Institute The novel oral drug venetoclax can be safely added to standard therapies for some high-risk myeloid blood cancers and in early studies the combination shows promise of improved outcomes, say scientists from Dana-Farber Cancer Institute. Venetoclax targets cancer’s survival proteins, making them more vulnerable to treatments […]

New simulation finds max cost for cost-effective health treatments — ScienceDaily

As health care costs balloon in the U.S., experts say it may be important to analyze whether those costs translate into better population health. A new study led by a Penn State researcher analyzed existing data to find a dividing line — or “threshold — for what makes a treatment cost-effective or not. David Vanness, […]

In rodent experiments modeled to mimic real-life circumstances, scientists revealed brain mechanisms that could lead to targeted treatments. — ScienceDaily

Through intricate experiments designed to account for sex-specific differences, scientists at Scripps Research have collaborated to zero in on certain changes in the brain that may be responsible for driving alcohol abuse among people with post-traumatic stress disorder, or PTSD. In studies with rodents, researchers found that males and females exhibit their own distinct symptoms […]