Pharmacology – An unconventional ion channel

Scientists at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified the first mechanosensitive ion channel to be found in an intracellular vesicle system. It responds to concentration changes within the vesicle, and probably controls the initiation of immune reactions. Small membrane vesicles, known as endosomes or lysosomes play a key role in the uptake, secretion and intracellular […]