How do viruses protect their genetic information?

Researchers uncover the mystery of how viruses avoid encapsulating unwanted genetic material from the crowded cell cytoplasm. Image credit: Juan Gaertner/Science Photo Library Understanding the intricate mechanisms behind viral infections is crucial to fighting them — as evidenced by the current global pandemic caused by the SARS-CoV-2 virus. Intensive research efforts have gone into understanding […]

Unravelling the mystery that makes viruses infectious — ScienceDaily

Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus ‘package up’ their genetic code, allowing them to infect cells. The findings, published today (Friday, 8 January) in the journal PLOS Pathogens by a team from the Universities of Leeds and York, open up the possibility that […]

Unravelling the mystery that makes viruses infectious

IMAGE: Capsid protein pentamers (subunits colour-coded) being recruited to the growing protein shell (brown) during virion assembly by formation of sequence-specific contacts between the genome (packaging signals shown as orange space-filled… view more  Credit: University of Leeds Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus ‘package […]

Unravelling the mystery that makes viruses infectious

Capsid protein pentamers (subunits colour-coded) being recruited to the growing protein shell (brown) during virion assembly by formation of sequence-specific contacts between the genome (packaging signals shown as orange space-filled models) and the Enterovirus-E capsid. Credit: University of Leeds Researchers have for the first time identified the way viruses like the poliovirus and the common […]

How epithelial cells ward off viruses

A keratinocyte cell line following infection with the Semliki Forest Virus (cell nuclei are shown in blue, and double-stranded RNA is stained in green). Credit: Stefan Bauernfried A team led by LMU’s Veit Hornung has shown that a protein found in skin cells recognizes a specific nucleic acid intermediate that is formed during virus replication. […]

Grabbing viruses out of thin air

Developments in pathogen-detecting materials could provide an easy means of detecting viruses within public places. Image credit: Davyn Ben on Unsplash The spread of COVID-19 has changed the lives of people around the world and has had a major impact on our daily lives. Other viruses have emerged suddenly from obscurity, such as Ebola, avian […]

Once-discounted binding mechanism may be key to targeting viruses — ScienceDaily

“Position 4” didn’t seem important until researchers took a long look at a particular peptide. That part of the peptide drawn from a SARS-CoV virus turned out to have an unexpected but significant influence on how it stably binds with a receptor central to the immune system’s ability to attack diseased cells. In a study […]

How animals can help us demystify viruses

Bats get a bad rap as viral vectors, but there are plenty of other animals that play a role in the rise and spread of infectious agents. (Walter Navarro/Pixabay/) As told to Sandra Gutierrez G. The COVID-19 origin story is murky at best. Epidemiologists agree that the disease likely thrived in bats before it made […]