When will COVID-19 vaccines start to make a difference?

COVID-19 vaccines should dramatically drive down the rate of new cases, hospitalizations and deaths in the U.S. — provided that enough people get the shots.

According to a new model, posted Nov. 30 to the preprint database medRxiv, vaccinating just 40% of the U.S. population would cut the attack rate, or new infections from the virus, more than four-fold over the course of one year. That reduction would occur both by directly protecting those who get the shots and indirectly protecting others in the wider community. 

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